Prevnar 13 Overview: Uses Dosage Side Effects And More
Prevnar 13 protects against sickness caused by a bacteria called Streptococcus pneumoniae, also known as pneumococcus.
Prevnar 13 was developed for infants and children. The CDC recommends that infants and children younger than 2 years of age get Prevnar 13, but some adults should get it too.
Studies show that at least one dose of Prevnar 13 protects more than 80% of babies from serious pneumococcal infections.
Prevnar 13 is a common vaccine for most U.S. newborns. In fact, its among the first few vaccines that most children receive in their lifetime. This widespread use is for good reason it helps prevent sickness caused by a bacteria called Streptococcus pneumoniae. This is often simply called pneumococcus.
Every year in the U.S., pneumococcal bacteria cause thousands of potentially deadly infections. This includes illnesses like pneumonia, meningitis, and bloodstream infections. Fortunately, we have a few tools to help protect against these serious conditions. Prevnar 13 is one of these tools.
Here, well talk about Prevnar 13 what it is, how effective it is, and side effects to be aware of.
What Are Side Effects Of Prevnar 13
Side effects with pneumococcal vaccines are usually mild and go away on their own within a few days. But, like with all vaccines, a number of side effects are possible.
Common side effects of Prevnar 13 include:
Pain, redness, or swelling at the injection site
Muscle and joint pain
Of note, side effects can be different for various age groups. Infants, older children, and adults can all have different side effects compared to people of other ages. For more information, talk to a pharmacist, pediatrician, or healthcare provider.
My Patient Is Allergic To Egg How Can They Receive A Flu Vaccine Safely
Based on prospective and retrospective studies of influenza vaccination in those with and without egg allergy , the presence of egg allergy does not increase the risk of allergic reactions to the influenza vaccine. Egg-based influenza vaccines can be administered in community vaccination clinics , General Practitioner surgeries or immunisation clinics, as a single dose followed by the recommended 15 minute observation period. It is not necessary to preferentially administer cell-based influenza vaccines in this patient group. For further information refer to MVEC: Allergy and immunisation.
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How Is Prevnar 13 Given
Prevnar 13 is given as an injection into a muscle.
For infants and toddlers, the pneumococcal 13-valent vaccine is given in a series of shots. The first shot is usually given when the child is 6 weeks to 2 months old. The booster shots are then given at 4 months, 6 months, and 12 to 15 months of age.
If your child is 7 months to 5 years old, he or she can still receive Prevnar 13 on the following schedule:
Age 7-11 months: Two shots at least 4 weeks apart, followed by a third shot after the child turns 1 year .
Age 12-23 months: Two shots at least 2 months apart.
Age 24 months to 5 years : One shot.
The timing of this vaccination is very important for it to be effective. Your child’s individual booster schedule may be different from these guidelines. Follow your doctor’s instructions or the schedule recommended by your local health department.
For adults and children older than 5 years, Prevnar 13 is usually given as one shot.
Be sure to keep your child on a regular schedule for other immunizations such as diphtheria, tetanus, pertussis , hepatitis, and varicella . Your doctor or state health department can provide you with a recommended immunization schedule.
Why The Recommendations Changed
Both the CDC and AAP say safety data and a need to catch up children and teens on missed vaccinations played a role.
“The AAP supports giving other childhood and adolescent immunizations at the same time as COVID-19 vaccines, particularly for children and teens who are behind on their immunizations, the AAPs statement reads. Between the substantial data collected on the safety of COVID-19 vaccines, and the extensive experience with non-COVID-19 vaccines which shows the immune response and side effects are generally similar when vaccines are given together as when they are administered alone, the benefits of co-administration and timely catch up on vaccinations outweigh any theoretical risk.
Woodworth also said that updated co-administration recommendations may facilitate catch up vaccination of adolescents. She cited data that showed the administration of many other vaccines has declined during the pandemic.
Specifically, vaccine orders from providers were down 11.7 million doses as of May 2, 2021 when compared with 2019. The gap was largest in vaccines usually given to teens, including:
- The Tdap vaccine
- HPV vaccine
- Meningococcal conjugate vaccine
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Who Should Have The Pneumococcal Vaccine
Anyone can get a pneumococcal infection. But some people are at higher risk of serious illness, so it’s recommended they’re given the pneumococcal vaccination on the NHS.
- adults aged 65 or over
- children and adults with certain long-term health conditions, such as a serious heart or kidney condition
Babies are offered 2 doses of pneumococcal vaccine, at 12 weeks and at 1 year of age.
People aged 65 and over only need a single pneumococcal vaccination. This vaccine is not given annually like the flu jab.
If you have a long-term health condition you may only need a single, one-off pneumococcal vaccination, or a vaccination every 5 years, depending on your underlying health problem.
Before Taking This Medicine
You should not receive Prevnar 13 if you ever had a severe allergic reaction to a pneumococcal or diphtheria toxoid vaccine.
Tell the vaccination provider if you or the child has:
a bleeding or blood clotting disorder such as hemophilia or easy bruising or
a weak immune system .
Before your child receives Prevnar 13, tell your doctor if the child was born prematurely.
You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving Prevnar 13.
Tell the vaccination provider if you are pregnant or breastfeeding.
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When Should You Schedule Your Vaccines
Older adults should get their flu shots in September or October, ideally by the end of October, according to the CDC. That’s because people lose immunity over time, and the vaccine components are updated annually to reflect which strains will be seen in the upcoming year.
You can get pneumococcal, shingles, and Tdap vaccines year-round. If you want to get them in the fall when you get your flu shot, talk to your doctor. These vaccines can be given with most types of flu vaccines.
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Can The Influenza Vaccine Be Given At The Same Time As Other Vaccines
Yes. Influenza vaccines can be co-administered with other vaccines. This includes pneumococcal, meningococcal, COVID-19 and live vaccines, as well as concurrently administering a Boostrix® vaccine to pregnant women.
The only exception to this is the co-administration of Fluad®Quad and Shingrix. Whilst co-administration of these vaccines is acceptable, there is limited safety data on this and therefore it is preferred to .
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Children At High Risk Of Ipd
Infants at high risk of IPD due to an underlying medical condition should receive Pneu-C-13 vaccine in a 4 dose schedule at 2 months, 4 months and 6 months followed by a dose at 12 to 15 months of age. Table 3 summarizes the recommended schedules for Pneu-C-13 vaccine for infants and children at high risk of IPD due to an underlying medical condition by pneumococcal conjugate vaccination history.
In addition to Pneu-C-13 vaccine, children at high risk of IPD due to an underlying medical condition should receive 1 dose of Pneu-P-23 vaccine at 24 months of age, at least 8 weeks after Pneu-C-13 vaccine. If an older child or adolescent at high risk of IPD due to an underlying medical condition has not previously received Pneu-P-23 vaccine, 1 dose of Pneu-P-23 vaccine should be administered, at least 8 weeks after Pneu-C-13 vaccine. Children and adolescents at highest risk of IPD should receive 1 booster dose of Pneu-P-23 vaccine refer to Booster doses and re-immunization. Refer to Immunocompromised persons for information about immunization of HSCT recipients.
Table 3: Recommended Schedules for Pneu-C-13 Vaccine for Children 2 months to less than 18 years of age, by Pneumococcal Conjugate Vaccination History
|Age at presentation for immunization||Number of doses of Pneu-C-7, Pneu-C-10 or Pneu-C-13 previously received|
Pneumonia Vaccine And Meningococcal Conjugate Vaccine
You cant give the PCV13 pneumonia shot with a meningococcal conjugate vaccine, as they may interfere with your bodys immunologic response to PCV13, the CDC warns.
There are two meningitis vaccines available in the United States: meningococcal conjugate and MenACWY. Theres also a vaccine against meningitis B. All 11- and 12-year-olds should get a MenACWY vaccine, with a booster dose at age 16.
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What Are The Possible Side Effects Of Pneumococcal Immunisation
All medicines and vaccines can have side effects. Sometimes they are serious, most of the time theyre not.
For most people, the chance of having a serious side effect from a vaccine is much lower than the chance of serious harm if you caught the disease.
Talk to your doctor about possible side effects of pneumococcal vaccines, or if you or your child have symptoms after having a pneumococcal vaccine that worry you.
Common side effects of pneumococcal vaccines include:
- pain, redness and swelling where the needle went in
- reduced appetite
- body aches.
Are There Any Other Pneumonia Vaccines
In addition to Prevnar 13 and Pneumovax 23, a couple of other pneumococcal vaccines have been recently approved. This includes Prevnar 20 and Vaxneuvance .
Prevnar 20 was FDA-approved in for people 18 and older. It protects against 20 different types of pneumococcal bacteria. Read more about Prevnar 20 in a previous GoodRx Health article.
Vaxneuvance was FDA-approved in for people 18 and older. This approval makes it the fourth pneumococcal vaccine thats approved for use. Read more about Vaxneuvance in another previous GoodRx Health article.
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What Is Prevnar 13 And Who Should Get It
As mentioned, Prevnar 13 is a vaccine that helps protect against sickness caused by pneumococcal bacteria. Its considered to be a conjugate vaccine, so its often abbreviated to PCV13.
Specifically, it helps protect against 13 types of the bacteria this is where the number in the vaccines brand name comes from. These are the 13 pneumococcal bacteria strains that are most likely to cause serious health problems.
By protecting against these bacteria, the vaccine helps prevent many illnesses. These include:
Pneumonia: This is a lung infection. Its usually caused by viruses or bacteria.
Meningitis: This is an infection that affects the tissue surrounding the brain and spinal cord. It can be caused by many things, such as bacteria, viruses, or fungi.
Bloodstream infections: Also called bacteremia, this is a condition in which bacteria enters your bloodstream. Left untreated, this can be very dangerous and affect multiple parts of your body.
Sinus infections: Chances are youve had a sinus infection at some point in your life. Theyre usually caused by viruses, but occasionally theyre caused by bacteria like pneumococcus.
Ear infections: Like sinus infections, many ear infections are caused by viruses. But some are also caused by bacteria like pneumococcus.
Because of these risks, the Centers for Disease Control and Prevention recommends that most people should get Prevnar 13 at some point in their life.
Do Immunosuppressed People Require 2 Doses Of Influenza Vaccines
People with certain immunocompromising conditions should receive 2 doses, a minimum of 4 weeks apart, of QIV formulation of influenza vaccine in the first year of being immunosuppressed. Only 1 dose is required annually thereafter. An exception to this is patients receiving high-immunogenicity vaccines where only 1 dose is recommended .
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Can Influenza Vaccines Be Given To Someone Who Has Had Guillain
Influenza vaccination has been identified as a possible cause of GBS following H1N1 containing vaccines, but the evidence is variable and at a very low rate, lower than the rate of GBS caused by wild type influenza. As per the AusVaxSafety clinical resources flow chart, influenza immunisation is generally not recommended for people with a history of GBS occurring within 6 weeks of receiving a previous influenza vaccine. However specialist immunisation advice should be sought to discuss the potential benefit of vaccination and the risk for GBS recurrence post vaccination or GBS recurrence post influenza disease. There are no concerns administering influenza vaccines to patients who have a history of developing GBS more than 6 weeks following an influenza vaccine.
Consider Timing For Coadministration
Flu vaccinations should be offered by the end of October. And for children who need two doses, they should receive their first dose as soon as possible after the vaccine is available because they cant have the second dose until at least four weeks later. The timing of the onset and peak of influenza activity varies from season to season. Within a particular season, this can also vary geographically with localized pockets of activity in some portions of the country are seen before others in any given season.
Over 36 seasons between 1982 and 2018, peak flu activity varied widely. It happened in December and March in 19% of seasons, while it occurred in February in 42% of the seasons. Vaccination should continue throughout the season, as long as influenza viruses are circulating and unexpired vaccine is available.
The AMA has developed frequently-asked-questions documents on COVID-19 vaccination covering safety, allocation and distribution, administration and more. There are two FAQs, one designed to answer patients questions , and another to address physicians COVID-19 vaccine questions .
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Should You Get A Flu Shot
In general, every person with diabetes needs a flu shot each year. Talk with your doctor about having a flu shot. Flu shots do not give 100% protection, but they do make it less likely for you to catch the flu for about six months.
For extra safety, it’s a good idea for the people you live with or spend a lot of time with to get a flu shot, too. You are less likely to get the flu if the people around you don’t have it.
The best time to get your flu shot is beginning in September. The shot takes about two weeks to take effect.
If youre sick , ask if you should wait until you are healthy again before having your flu shot. And don’t get a flu shot if you are allergic to eggs.
You are advised to continue to take the general precautions of preventing seasonal flu and other communicable illnesses and diseases:
- Cover your nose and mouth with a tissue when you cough or sneeze. Throw the tissue in the trash. If you dont have a tissue, cough or sneeze into your elbow, not your hand.
- Wash your hands often with soap and water, especially after you cough or sneeze. Alcohol-based hand cleaners are also effective.
- Avoid touching your eyes, nose, or mouth. Germs spread that way.
- Try to avoid close contact with sick people.
- If you get sick, stay home from work or school and limit contact with others to keep from infecting them.
Prevnar 13 Side Effects
Get emergency medical help if you have signs of an allergic reaction to Prevnar 13: hives difficult breathing swelling of your face, lips, tongue, or throat.
You should not receive a booster vaccine if you had a life threatening allergic reaction after the first shot.
Keep track of all side effects you have. If you need a booster dose, you will need to tell the vaccination provider if the previous shot caused any side effects.
Becoming infected with pneumococcal disease is much more dangerous to your health than receiving Prevnar 13. However, like any medicine, Prevnar 13 can cause side effects but the risk of serious side effects is low.
sleeping more or less than usual
swelling, tenderness, or redness where a shot was given
trouble moving the arm where a shot was given
crying or fussiness
vomiting, loss of appetite or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.
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What Side Effects Should I Watch For
Side effects vary from vaccine to vaccine, according to Privor-Dumm.
- Pain, swelling, redness, or soreness at the injection site
- A low-grade fever
- Muscle aches
In very rare cases, you may be allergic to the ingredients in a vaccine or have another severe reaction. If you feel sick in any way after receiving a shot, call your doctor, Privor-Dumm says.
Encourage Patients To Get Flu And Pneumococcal Vaccines
Pharmacists play a critical role in protecting patients from seasonal influenza and pneumonia illnesses and sequelae.
Pharmacists position as accessible health care professionals affords them the ideal opportunity to remind patients to stay up-to-date on immunizations.
Every season, pharmacies embark on a major outreach to immunize the public against influenza and pneumonia. It is imperative that pharmacists understand the recommendations put forth by the CDC for each seasons vaccines. Pharmacists also need to know which vaccines are available be able to combat misconceptions about vaccines and, by making strong recommendations, help increase the number of patients receiving these immunizations.
The inuenza virus infects the lungs, nose, and throat, causing a highly contagious respiratory illness. Flu symptoms can be mild to severe, leading to hospitalization and possibly death.
Anyone can get the flu, which can cause serious problems at any age. However, some people are at increased risk of complications, such as the elderly pregnant women those with chronic medical conditions, such as asthma, diabetes, or heart disease and young children.
The CDC recommends that everyone older than 6 months receive the inuenza vaccine every year. The agency also advises immunizing from the end of August through October to achieve the greatest benet, based on the months that most cases of inuenza develop.
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