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“The most concerning products are those that contain decongestants, because they constrict or narrow blood vessels, which can raise blood pressure,” says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital. When you have a cold, your body sends extra blood to your nose. The blood vessels and nearby tissues swell, causing congestion or a stuffy nose. But if you take a decongestant, it affects all your blood vessels, not just those in your nose. Thats why its safest to avoid products that contain oxymetazoline , pseudoephedrine , and phenylephrine .
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When you have a cold or an allergy attack, your white blood cells gather in your nasal passages and sinuses. This causes nasal membranes to swell and increases mucus production. Pseudoephedrine constricts these blood vessels, which decreases drainage.
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Pharmacist Kayla Ryan explains the mechanism of pseudoephedrine. Pseudoephedrine is chemically similar to adrenaline, so the body recognizes it as adrenaline, causing the blood pressure and heart rate to increase.
She refers to one of the last major studies of the effects of pseudoephedrine on blood pressure, which took place in 2005. This study found that pseudoephedrine increased systolic blood pressure by one point on average, while heart rate increased by an average of three beats per minute.
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In 2005, the FDA passed the Combat Methamphetamine Act, which requires pharmacies to sell all medications containing pseudoephedrine behind the counter. At your local drugstore, youll find cards in the cold and flu aisle with information for these medications. You can take the card to the pharmacist, who is required to scan your drivers license before purchase.
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