How To Use Tylenol Cold
See also Warning section.
If you are taking the over-the-counter product, read all directions on the product package before taking this medication. If you have any questions, consult your pharmacist.
Take this medication by mouth with or without food or as directed by your doctor. This medication can be taken with food or milk if stomach upset occurs.
If you are using a liquid form, carefully measure your prescribed dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.
Chewable forms of this medication should be chewed thoroughly before swallowing.
The dosage is based on your age. Do not increase your dose or take this medication more often than directed without your doctor’s approval. Improper use of this medication may result in serious harm .
Tell your doctor if your condition persists for more than 1 week, if it worsens, or if it occurs with rash, persistent headache, or fever lasting more than 3 days. These may be symptoms of a serious medical problem and should be checked by a doctor.
Tips For Cold And Flu Symptoms
Although you may try your best to avoid seasonal colds and flu, there are lots of ways to get ready for when they come up.
Please note that this content is not intended as professional medical or healthcare advice and is not intended as a substitute for professional healthcare advice, or services from a qualified healthcare provider such as a physician, pediatrician or other professional familiar with your unique situation. This content is intended solely as a general product and educational aid. If you have any questions, please consult your physician or pharmacist.
Do You Have A Cold Or The Flu
You feel a tickle in your throat, and then a headache coming on. You start to sniffle or sneeze, and suddenly you feel really tired. You know youre coming down with something but is it a cold, or do you have the flu?
With both conditions your symptoms can include a sore throat, runny nose, headache, body aches, chills, fatigue, nausea, vomiting and sometimes diarrhea, says Dr. Denise Campbell-Scherer, an associate professor in the department of family medicine at the University of Alberta. The main difference is that with the flu, youll have a temperature above 37.8°C. Flu symptoms also tend to come on suddenly, are more severe and are at their worst for the first three or four days after that, it can take up to two weeks before you feel better. A cold can linger anywhere from a few days to a few weeks, although one week is typical.
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What Are Some Other Side Effects Of This Drug
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling nervous and excitable.
- Not able to sleep.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
What Is Tylenol Cold & Flu Severe

Acetaminophen is a pain reliever and fever reducer.
Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion .
Tylenol Cold & Flu Severe is a combination medicine used to treat headache, fever, body aches, cough, chest congestion, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.
Tylenol Cold & Flu Severe will not treat a cough that is caused by smoking, asthma, or emphysema.
Tylenol Cold & Flu Severe may also be used for purposes not listed in this medication guide.
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Cold And Flu Warning: The Dangers Of Too Much Acetaminophen
- By Susan Farrell, MD, Contributing Editor
Cold and flu season is here.
Peruse the aisles of a local pharmacy or grocery store and you will find more than 30 over-the-counter medications available to treat the symptoms of fever, headache, sore throat, and achy muscles. Many of these multi-symptom products contain acetaminophen, the active ingredient in Tylenol. This means cold and flu sufferers who are using multiple combination cough and cold remedies may inadvertently be taking more acetaminophen than they intend and putting themselves at risk for a serious complication: acetaminophen-induced liver toxicity.
Acetaminophen is the most commonly available pain-relieving and fever-reducing medication. It is an ingredient in more than 600 over-the-counter and prescription medications, and it has a remarkable safety profile: the dose at which potential toxicity occurs is dramatically higher than the amount that most adults need to effectively treat their symptoms . Moreover, acetaminophen does not cause the unwanted effects that are associated with non-steroidal anti-inflammatory drugs or prescription opioids. As a result, acetaminophen is known as a very safe and effective over-the-counter medication for the treatment of pain and fever, and is taken by millions of people.
Exceeding The Recommended Acetaminophen Dosage
An estimated 50 million Americans use acetaminophen each week to treat conditions such as pain, fever and aches and pains associated with cold and flu. To help encourage the safe use of acetaminophen, the makers of TYLENOL® in 2011 lowered the maximum daily dose for single-ingredient Extra Strength TYLENOL® products sold in the U.S. from 8 pills per day to 6 pills per day . The dosing interval has also changed from 2 pills every 46 hours to 2 pills every 6 hours.
In case of overdose, you should get medical help right away or contact the Poison Control Center at 1-800-222-1222. Quick medical attention is critical for adults as well as for children even if no signs or symptoms are noticed.
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Tylenol Dosage For Adults
TYLENOL® is the #1 Doctor Recommended Brand for pain relief and fever reduction. TYLENOL® products contain the active ingredient acetaminophen and are formulated to temporarily reduce fever and relieve minor aches and pains.
Below you will find dosing charts for several adult TYLENOL® products available in different forms including tablets, liquid gels and dissolve packs with information for the maximum dose. Use these dosing charts as your guide to ensure safe use.
2 tablets every 4-6 hours while symptoms last
Not to exceed 10 tablets in 24 hours, unless directed by a doctor
2 capsules every 4-6 hours while symptoms last
Not to exceed 10 capsules in 24 hours, unless directed by a doctor
2 caplets every 6 hours while symptoms last
Not to exceed 6 caplets in 24 hours, unless directed by a doctor
2 tablets every 6 hours while symptoms last
Not to exceed 6 tablets in 24 hours, unless directed by a doctor
2 gelcaps every 6 hours while symptoms last
Not to exceed 6 gelcaps in 24 hours, unless directed by a doctor
2 caplets every 8 hours while symptoms last
Not to exceed 6 caplets in 24 hours, unless directed by a doctor
2 caplets every 8 hours while symptoms last
Not to exceed 6 caplets in 24 hours, unless directed by a doctor
2 powders every 8 hours while symptoms last
Not to exceed 6 powders in 24 hours, unless directed by a doctor
Tylenol Cold + Flu Severe Day/night Liquid Medicine 8 Fl Oz
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Item No. 0385029
Temporarily relieve multiple cold and flu symptoms both day and night with Tylenol Cold + Flu + Cough Severe Liquid Medicine Value Pack. This two-pack contains one bottle of liquid non-drowsy daytime relief and one bottle of liquid nighttime relief. The daytime flu relief for adults features a powerful non-drowsy formula to keep you going through waking hours with a warming honey lemon flavor. The nighttime liquid medicine relieves symptoms to help you sleep and comes in a soothing berry flavor. The liquid medicines both provide temporary relief of cold & flu symptoms including fever, cough, nasal and chest congestion, headache, body aches and sore throat. They also aid in loosening mucus & thinning bronchial secretions for more productive coughs. Both of these effective cold relievers are formulated with acetaminophen, phenylephrine HCl, guaifenesin, and dextromethorphan HBr cough suppressant. The nighttime formula also contains doxylamine succinate, an antihistamine.
No |
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Tylenol Cold & Flu Severe Side Effects
Get emergency medical help if you have signs of an allergic reaction:hives difficult breathing swelling of your face, lips, tongue, or throat.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.
Stop using this medicine and call your doctor at once if you have:
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chest pain, fast, slow, or uneven heart rate
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severe dizziness, feeling like you might pass out
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mood changes, confusion, hallucinations
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fever
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urinating less than usual or not at all
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nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice or
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dangerously high blood pressure .
Common side effects may include:
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dizziness, weakness
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dry mouth, nose, or throat
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feeling nervous, restless, irritable, or anxious or
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sleep problems .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What Should I Avoid While Taking Tylenol Cold & Flu Severe
Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen.
Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
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What Other Drugs Will Affect Tylenol Cold & Flu Severe
Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.
Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking acetaminophen, dextromethorphan, and phenylephrine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tylenol Cold + Flu Severe Multi

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Before Taking This Medicine
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
You should not use this medication if you are allergic to acetaminophen, dextromethorphan, guaifenesin, or phenylephrine.
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:
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liver disease, alcoholism, or if you drink more than 3 alcoholic beverages per day
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enlarged prostate or urination problems
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cough with mucus, or cough caused by emphysema or chronic bronchitis
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overactive thyroid.
It is not known whether Tylenol Cold & Flu Severe will harm an unborn baby. Do not use this medicine without a doctor’s advice if you are pregnant.
Acetaminophen, dextromethorphan, guaifenesin, and phenylephrine may pass into breast milk and may harm a nursing baby. may also slow breast milk production. Do not use this medicine without a doctor’s advice if you are breast-feeding a baby.
Artificially sweetened liquid medicine may contain phenylalanine. Check the medication label if you have phenylketonuria .
What Are Some Side Effects That I Need To Call My Doctor About Right Away
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash hives itching red, swollen, blistered, or peeling skin with or without fever wheezing tightness in the chest or throat trouble breathing, swallowing, or talking unusual hoarseness or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Not able to pass urine or change in how much urine is passed.
- A very bad skin reaction may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin red or irritated eyes or sores in your mouth, throat, nose, or eyes.
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How To Use Tylenol Cold And Flu Oral
See also Warning section.
If you are taking the over-the-counter product, read and follow all directions on the package label. If your doctor has prescribed this medication for you, take as directed by your doctor. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food or as directed by your doctor. If stomach upset occurs, it may help to take this medication with food or milk. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. The fluid will help loosen the mucus in your lungs.
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.
If you are taking extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
If you are taking the chewable form of this medication, chew it thoroughly before swallowing.
To Relieve A Sore Throat Fever Headache Or Muscle Aches
Examples: Motrin Tablets Advil Caplets Aspirin Original Strength Tylenol Regular Strength Tablets
How they work: Non-steroidal anti-inflammatory drugs , which include ibuprofen and acetylsalicylic acid , work by preventing the formation of prostaglandins, the chemicals in the body that promote pain, inflammation, and fever. Acetaminophen, found in Tylenol, behaves slightly differently it targets the part of the brain that perceives pain and controls body temperature. Both types are equally effective, says Kalyn, so its just a matter of balancing the benefits versus the risks.
NSAIDs will reduce symptoms for six to eight hours compared to four to six for acetaminophen, so NSAIDs can be more beneficial if you need help sleeping through the night.
Need to know: Follow package directions for dosing. The most common adverse effect with NSAIDs is stomach discomfort, so take them with food, says Kalyn. Avoid NSAIDs if you have high blood pressure, a heart, liver or kidney condition, or stomach issues such as heartburn. NSAIDs can increase the risk of ulcers, internal bleeding and damage to the heart, liver, and kidneys. Aspirin should not be taken by those on blood thinners and has been linked to Reyes syndrome, so it should not be given to people age 18 and under. Avoid Tylenol if you have liver or kidney disease.
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How To Use Tylenol Cold And Flu Severe 5 Mg
See also Warning section.
If you are using the over-the-counter product, read and follow all directions on the product package before taking this medication.
Take this medication by mouth with or without food, usually every 4 to 6 hours as needed, or as directed by your doctor. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. The fluid will help loosen the mucus in your lungs.
If you are using a liquid form, carefully measure your dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. For some liquid products, you may need to shake the bottle well before each dose. Check the directions on the product package.
The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed without your doctor’s approval. Improper use of this medication may result in serious harm .
Tell your doctor if your condition persists for more than 5 to 7 days, if it worsens, or if it occurs with rash, persistent headache, or fever lasting more than 3 days. These may be symptoms of a serious medical problem and should be checked by a doctor.